Optimizing Chamber Humidity Control

Amira, an Italian-based company that produces devices and machines for the pharmaceutical industry and research centers, needed a highly reliable and robust humidity sensor for their BioReset line of bio-decontamination products. Amira's BioReset line offers bio-decontamination solutions using hydrogen peroxide vapor, a technology capable of eradicating a wide range of bacteria, viruses, and moulds at low temperatures without negatively affecting the treated environment. The gaseous state of hydrogen peroxide minimizes its corrosive effects.

Rotronic HygroClip2 Probes

To ensure that the vapor does not re-condense, Amira integrated the Rotronic HygroClip2 probes into their solutions. These sensors accurately monitor temperature, humidity, and dewpoint inside treated rooms. The probes are resistant to the corrosive effects of hydrogen peroxide, making them ideal for Amira's bio-decontamination solutions.

Reliability and Precision

Angelo Delmiglio, founder and CEO of Amira, valued Rotronic reliability and precision for over 25 years. The Rotronic HygroClip2 probes, with their corrosion-resistant housing and extreme precision, are ideally suited for the pharmaceutical industry.

Conclusion

International pharmaceutical companies rely on Amira's bio-decontamination solutions, and Rotronic high-quality instruments to contribute to their success. By using the Rotronic HygroClip2 probes in their BioReset line, Amira ensures that their customers' expectations are met with precise and reliable decontamination processes.

Totech GmbH, a leading company in drying cabinets, dry-storage cabinets, vacuum units, and nitrogen cabinets. For their latest dynamic drying unit and stability range Totech required a stable and accurate humidity control solution. Totech chambers are used to assess the shelf life, potency, and safety of their pharmaceutical products under various closely controlled environmental conditions.

This dynamic drying unit achieves humidity values below 0.17 %RH at 60 °C, maintaining a low energy consumption and providing tailored solutions for various applications.

Adaptive Drying Process

Totech's storage systems create an atmosphere with <0. 5%RH at room temperature and a water vapor content of less than 0.05 g/m³, effectively re-drying moisture-sensitive components and circuit boards without causing thermal stress. The dynamic drying unit is the core of this process, providing a "moisture vacuum" that quickly extracts moisture from the components.

Energy-Efficient and Responsive

Unlike previous models that required regular regeneration of the drying agent, the new design dynamically adapts the regeneration process based on the drying agent's condition, continuously monitored by a microprocessor. Thermal regeneration is initiated only when necessary, reducing energy consumption and ensuring the drying unit remains effective for extended periods.

Precise Humidity Measurement with Rotronic Sensors

A key prerequisite for controlling the regeneration process is accurate, long-term stable humidity measurement. Totech relies on the Rotronic fast-responding HygroClip2 probe to provide precise and stable humidity data. The integrated data logger records humidity and temperature data continuously in offline mode, while the data can also be stored online via the standard serial port for real-time monitoring and documentation.

Conclusion

The reliable connector of the Rotronic probe allows for easy recalibration, ensuring the entire system remains accurate and reliable. By combining Totech's maintenance-free drying units with Rotronic precision probes, this advanced drying solution achieves high de-moisturizing performance and energy efficiency for moisture-sensitive components.

Steriline, a Northern Italian pharmaceutical equipment manufacturer, specializing in the production of high-quality equipment for the pharmaceutical industry. Steriline are focused on the development and production of highly technological and distinct solutions including isolators. Isolators are used in pharmaceutical for quality control, sterility testing, and wherever precise monitoring and control of various environmental conditions, including temperature and humidity, are required.

Quality Principles and Controlled Manufacturing

Steriline's success is based on fundamental quality principles, including reliability and precision, which they maintain throughout their manufacturing process. The company develops and produces highly technological solutions, such as isolators for quality control and sterility testing, where precise monitoring and control of various environmental conditions are crucial.

Temperature and Humidity Measurement with Rotronic

Temperature and humidity are two key environmental variables that Steriline needs to monitor. They use Rotronic instruments such as the HygroFlex5, combined with HygroClip2 probes throughout their plant and, importantly, inside their isolators.